Side effects of trientine

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August undefined, 2024

WebYou may report side effects to Health Canada at 1-866-234-2345. Warnings & Precautions Before taking trientine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. WebTrientine (Syprine) is a chelating agent, which means that it attaches to certain metals to help remove them from the body. In Wilson's disease, high amounts of copper get stored …

Trientine Waymade Drug / Medicine Information - News-Medical.net

WebBackground & aims: Wilson disease is a genetic copper storage disorder that causes hepatic and neurologic symptoms. Chelating agents (D-penicillamine, trientine) are used as first-line therapies for symptomatic patients, but there are few data from large cohorts. We assessed the safety of D-penicillamine and trientine therapy and outcomes of ... WebChelating agents. Penicillamine (Cupramine, Depen) and trientine (Syprine) are two chelating agents used to treat Wilson disease. These medicines remove copper from the body. Penicillamine is more likely to cause side effects than trientine. Side effects of penicillamine may include fever, rash, kidney problems, or bone marrow problems. mountain view rehabilitation marysville wa

Update on the clinical management of Wilson

WebStudies in animals have shown that trientine hydrochloride has cupriuretic activities in both normal and copper-loaded rats. In general, the effects of trientine hydrochloride on urinary copper excretion are similar to those of equimolar doses of penicillamine, although in one study they were significantly smaller. Human Studies WebLess serious side effects Less serious side effects What to do Gastrointestinal related: • Nausea Other ingredients • Abdominal or stomach pain or discomfort Skin related: • Skin … WebIf experienced, these tend to have a Severe expression i. inflammation of the skin due to an allergy. hives. a skin rash. abnormal muscle movements. mountain view rehab in boulder city

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WebMay 11, 2024 · What is the dosage of Trientine? Adults: The recommended dose is 1.2 to 2.4 gm daily in 2 to 4 divided doses, before meals. Child: The dose is based on body weight. WebThis information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Brand Names: US. Clovique [DSC]; Syprine. Brand Names: Canada. MAR-Trientine; Waymade-Trientine. What is this drug used for? It is used to treat ... heart attack right arm numbWebSep 23, 2024 · Trientine Tillomed is given to adults, adolescents, and children aged 5 and over who cannot tolerate penicillamine, another medicine used to treat this disease. The … mountain view rehab ossipee nh

"WebThis effect is more common in patients treated with D-penicillamine and up to 50% of WD patients with neurologic presentation experience further deterioration that is often irreversible. 78 The same phenomenon is also observed with trientine therapy but its incidence is lower with 10%–15% patients experiencing progression of their neurologic ... " - Side effects of trientine

Side effects of trientine

Efficacy and safety of oral chelators in treatment of patients with ...

WebAug 1, 2024 · Trientine hydrochloride capsules should be used when continued treatment with penicillamine is no longer possible because of intolerable or life endangering side effects. Unlike penicillamine, trientine hydrochloride capsules are not recommended in cystinuria or rheumatoid arthritis. WebJan 12, 2024 · Serious side effects of Syprine. Along with its needed effects, trientine (the active ingredient contained in Syprine) may cause some unwanted effects. Although not …

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WebJan 8, 2024 · Overall, trientine has shown positive effects in in vitro genotoxicity studies, including the Ames test and genotoxicity tests in mammalian cells. In vivo, trientine was … WebRash was a commonly reported side effect of Cuvrior (trientine tetrahydrochloride) in the clinical studies. If you develop a rash or other allergic reaction during treatment with Cuvrior (trientine tetrahydrochloride), contact your provider to discuss whether you should continue taking it or switch to a different medication.

WebMay 9, 2024 · SIDE EFFECTS. Clinical experience with SYPRINE has been limited. The following adverse reactions have been reported in a clinical study in patients with Wilson's disease who were on therapy with trientine hydrochloride: iron deficiency, systemic lupus erythematosus (see CLINICAL PHARMACOLOGY).In addition, the following adverse … WebMar 12, 2024 · Trientine (Syprine) - Uses, Dose, MOA, Side effects, Brands. Trientine (Syprine) is a chelating agent that forms soluble complexes with copper, iron, and zinc resulting in its excretion via urine. It is used in the treatment of patients with Wilson's disease, especially those who are intolerant to penicillamine.

WebTablets: 300 mg of trientine tetrahydrochloride (equivalent to 150 mg of trientine), oblong, yellow coated, functionally scored, printed with OL75 on each side of score line in black ink. Each large carton contains nine . small cartons, each containing a blister pack of 8 tablets (a total of 72 tablets in the large carton). 4 CONTRAINDICATIONS WebOct 12, 2024 · Common side effects may include: heartburn, stomach pain, loss of appetite; black, tarry stools; general ill feeling; mouth sores; or. skin flaking, cracking, or thickening. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

WebJan 12, 2024 · Trientine side effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur …

WebJul 25, 2024 · Trientine is an oral copper chelating agent used to treat Wilson disease. ... (Four patients with primary biliary cirrhosis and elevated hepatic copper levels developed intolerable side effects within two weeks … heart attack risk quizWebIn Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Drug dosage regimens. Trientine and zinc have become major tools in the management of Wilson’s disease. Zinc (usually … heart attack risk calculator nhsWebMedscape - Wilson disease dosing for Cuvrior, Syprine (trientine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, … heart attack roblox idWebMay 11, 2024 · Cuvrior may cause serious side effects including: hives, difficulty breathing, swelling of your face, lips, tongue, or throat, abdominal pain, change in bowel habits, and. … heart attack risk assessment testWebWilson's disease. Adult: In patients who are intolerant of penicillamine: As trientine dihydrochloride cap: 1,200-2,400 mg daily in 2-4 divided doses. Alternatively, 750-1,250 mg daily in 2-4 divided doses (Max: 2,000 mg daily). As trientine tetrahydrochloride tab: 450-975 mg daily in 2-4 divided doses. Initiate at the lowest dose in the range ... heart attack rieslingWebFeb 28, 2024 · Trientine Waymade is used to treat Wilson’s disease in people who can not take another medicine called penicillamine because of side effects. Wilson’s Disease is a condition which results in ... heart attacks affect circulatory systemWebApr 23, 2024 · SIDE EFFECTS. Clinical experience with trientine hydrochloride has been limited. The following adverse reactions have been reported in a clinical study in patients … heart attack risk score