Irf7 mouse

Author: aowf

August undefined, 2024

WebJan 18, 2024 · It has been proposed, based on studies of mouse Ifna4 and Ifna2 genes , that late-phase expression of IFNA genes is controlled by Irf7 binding to VRE-A/B, whereas early-phase expression is controlled by Irf3 binding to VRE-C. We show that for many IFNs (63%, 17/27) it is only IRF7 that binds to VRE-A/B, suggesting that late-phase expression ... WebInterferon regulatory receptor 7 (IRF7) is a transcription factor involved in the activation of the type I interferon (IFN) response upon pathogenic infection [3-4]. IRF7 has been implicated downstream of several pattern recognition receptors (PRRs), including TLRs, RLRs, and DNA sensors [2].

IRF7 Polyclonal Antibody (PA5-20281) - Thermo Fisher Scientific

WebApr 7, 2005 · Consistently, Irf7-/- mice are more vulnerable than Myd88-/- mice to viral infection, and this correlates with a marked decrease in serum IFN levels, indicating the … WebImmunohistochemistry-Paraffin: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of paraffin-embedded mouse liver tissue using anti-IRF7 antibody. Counter stained with hematoxylin. Flow Cytometry: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of Jurkat cells with IRF7 antibody at 1/50 dilution (red) compared with an unlabelled control (cells ... chinnor paving supplies

DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: …

WebRestoration of IRF7 in tumor cells isolated from metastatic mouse primary mammary tumors restored the ability to secrete IFN and reduced the metastatic burden in a breast … WebProduct Details. Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. The antibody was purified by affinity chromatography. The antibody solution should be stored undiluted between 2°C and 8°C. WebPrimePCR™ Template for SYBR® Green Assay: Irf7, Mouse Reaction: 200 x 20 µl reactions desalted Gene-specific synthetic DNA template designed to give a positive real-time PCR … granite mining method

Plasmacytoid dendritic cells control dengue and Chikungunya …

IRF7 Polyclonal Antibody (PA5-20281) - Thermo Fisher Scientific

WebMar 7, 2024 · Here we used MLL-AF9-induced acute myeloid leukemia (AML) mouse models with IRF7 knockout or overexpression and xenograft mouse models to explore the … WebJan 10, 2024 · IRF7 is the key transcription factor which induces IFNα expression 9, leading to a second wave of type I IFN release. Since IFNα signals via the IFNAR this leads to a positive feedback loop that... chinnor parish councilWebIRF7 Antibodies Antibodies that detect IRF7 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry … chinnor photos

"WebJul 25, 2024 · By performing mass-spectrometry analysis of IRF3 and IRF7 isolated from cells treated with a SIRT1 inhibitor, we identified SIRT1-specific lysine-deacetylation sites and confirmed this result by... " - Irf7 mouse

Irf7 mouse

IRF7: activation, regulation, modification and function

WebIrf7 Name interferon regulatory factor 7 Feature Type protein coding gene IDs MGI:1859212 NCBI Gene: 54123 Alliance gene page Transcription Start Sites 17 TSS Location & Maps … WebJul 14, 2016 · IRF3-5D, an active form of IRF3, and IRF7Δ247–467, a constitutively active form of IRF7 were constructed as previously described using pFLAG-IRF3, and pFLAG-IRF7 plasmids as templates 38,39,40 ...

Did you know?

http://www.informatics.jax.org/allele/allgenoviews/MGI:3577089 IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. Multiple IRF7 tra…

WebPE Mouse anti-IRF-7 This SKU will be discontinuing June 2024. For additional support, contact your local applications specialist. Contact Us PE Mouse anti-IRF-7 Clone K40-321 (RUO) View all Formats Analysis of IRF-7 in transfected human epithelial cells. WebMay 21, 2024 · By combining DNA microarray and genomic data analyses to predict DNA binding motifs, we identified the transcription factor Interferon Regulatory Factor 7 (IRF7) as a possible regulator of genes related to adipocyte hypertrophy.

WebAug 21, 2024 · IRF-7 Antibody (G-8): sc-74472 IRF-7 Antibody (G-8) is a mouse monoclonal IgG 2a κ IRF-7 antibody, cited in 26 publications, provided at 200... IRF-7 Antibody (G-8) is … WebInterferon regulatory factor 7 (IRF7) is the main transcriptional regulator of type I IFN, and it is crucial for the induction of IFNα/β and the type I IFN-dependent immune response. In this study, we focused on the role of IRF7 in the pathogenicity and immunogenicity of RABV using an IRF7 -/- mouse model.

WebJul 7, 2024 · It remains possible that IRF7, a homolog of IRF3, compensates for the loss of IRF3 and explains the IRF3-independent resistance to HSV-1 that we observe. ... Mouse primary microglia cells and ...

WebMar 7, 2024 · AML-IRF7 −/− mice exhibited accelerated disease progression with intracerebral invasion of AML cells. AML-IRF7 −/− cells showed increased proliferation and elevated leukemia stem cell (LSC)... chinnor pavingWebPrimePCR™ PreAmp for SYBR® Green Assay: Irf7, Mouse Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis. chinnor places to eatWebIRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. For Research Use Only. chinnor planning applicationsWebNov 30, 2024 · IRF7 could regulate the transcription of Usp25 in mouse embryonic fibroblast (MEFs) and BM-derived dendritic cells (BMDCs) in response to viral infection or LPS. 42 It was reported that Usp25 binds with the promoter of Sox2 that played an important role in the pluripotency of embryonic stem cells development. 43, 44 Whether Usp25 is a potential ... granite modern office deskWebPhospho-IRF-7 (Ser437/438) (D6M2I) Rabbit mAb (Mouse Specific) recognizes endogenous levels of mouse IRF-7 protein when dually phosphorylated at Ser437 and Ser438. This … chinnor planningWebOct 18, 2024 · Interferon regulatory factor 7 (IRF7) is the main transcriptional regulator of type I IFN, and it is crucial for the induction of IFNα/β and the type I IFN-dependent immune response. In this... chinnor postcodeWebApr 13, 2024 · RNA sequencing analysis of IRF7 CRISPRa and CRISPRi- DF-1 cells revealed the specificity of CRISPRa and CRISPRi-based targeted transcriptional regulation with minimal off-target effects. ... Cox, T.; Melvin, D.; Wang, X.; Bradley, A.; Liu, P. Chromosomal transposition of PiggyBac in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA … chinnor pool