Human il-2 uniprot

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August undefined, 2024

WebApr 9, 2024 · This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine … WebProduct name Recombinant human IL-2 protein (Active) See all IL-2 proteins and peptides Biological activity The ED 50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 10 5 units/mg. Purity > 95 % SDS-PAGE. Endotoxin level < 1.000 Eu/µg Expression system

Human IL-2 Recombinant Protein (RIL2I) - Thermo Fisher Scientific

WebHuman IL-2 Protein (PHC0027) in FN. THP-1 cells were treated with 20 ng/mL of human IL-2 recombinant protein ( Product # PHC0023) for 24 hours. Western blot was performed … WebApr 4, 2024 · Tat. tat. HIV-1 Tat upregulates the expression of interleukin 15 (IL15) gene in mammary epithelial cells. PubMed. capsid. gag. Unactivated memory CD4+ T cells infected by HIV-1 in the presence of IL-2 and IL-15 alone or IL-6/IL-7/TNF-alpha combination, upregulate granzyme B and HIV-1 CA production. explain the 8 kinds of wellness from samhs

Interleukin-2 human (IL-2) H7041 - Sigma-Aldrich

WebSep 17, 2024 · The present invention relates to a pharmaceutical composition for enhancing immunity, and was arrived at by discovering that oligopeptide AQTGTGKT and an analog thereof have the effect of appropriately modulating immune activity in the body, such as by suppressing excessive immune response while enhancing immune activity for defending … WebIL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells, promoting proliferation and maturation. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. Product Details Technical data sheet Product Details WebDescripción general. Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulated T-cell-dependent immune reactions and control regulatory T cells or Tregs. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. explain the 8 wastes

Human IL-33 Recombinant Protein (200-33-1MG)

Human IL-2 Recombinant Protein - Thermo Fisher Scientific

IL2 Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic lineage Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo … See more WebHuman IL-2 ELISpot Pair Assay Genie ELISpot is a highly specific immunoassay for the analysis of IL-2 production and secretion from T-cells at a single cell level in conditions closely comparable to the in-vivo environment with minimal cell manipulation. explain the 8 millennium development goalsWebRecombinant human IL-2 is a non-glycosylated protein containing 134 amino acids. Recombinant human IL-2 has a Ser substitute for Cysteine at position 126. Reconstitute using sterile 10 mM HCl at 0.1 mg/mL and … explain the 8 healthy eating tips

"WebJul 2, 2002 · 1M47 Crystal Structure of Human Interleukin-2 PDB DOI: 10.2210/pdb1M47/pdb Classification: CYTOKINE Organism (s): Homo sapiens Expression System: Escherichia coli BL21 Mutation (s): No Deposited: 2002-07-02 Released: 2002-07-31 " - Human il-2 uniprot

Human il-2 uniprot

Recombinant Human IL-2 carrier-free - BioLegend

WebMay 23, 2024 · Cryo-EM structures of 11-2 F / MTA-bound human PRMT5/MEP50 complex and its apo form resolved at 3.1 and 3.2 Å respectively show that 11-2 F in the catalytic pocket shifts the cofactor-binding pocket away by ~2.0 Å, contributing to positive cooperativity. ... 2.1.1.320: UniProt & NIH Common Fund Data Resources: Find proteins … WebOct 3, 2006 · Function. Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal …

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WebInterleukin-2 (IL-2) is an α-helical cytokine belonging to T-helper cell type 1. It has a molecular weight of 15kDa. The IL2 gene is mapped to human chromosome 4q27. IL-2 … WebDescription Product name Recombinant human IL-2 protein (Active) See all IL-2 proteins and peptides Biological activity The ED50, as determined by the dose-dependent stimulation of murine CTLL-2 cells, is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10 7 units/mg. Purity >= 98 % SDS-PAGE. >=98% HPLC analyses. Sterile filtered.

WebDescription. Interleukin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 133 amino acids fragment (21-153) having a … Web(130-097-745) Human IL-2 IS, premium grade Sign in or register to save this reagent to your favourites Supplier Miltenyi Biotec Classification Cytokine Protein Name Interleukin-2 UniProt ID P60568 - IL2_HUMAN Species Homo sapiens (Human) Gene IL2 View Product On Supplier's Website Request a Quote from Miltenyi Biotec Supplier provided information

WebRecombinant Mouse IL-2 (Catalog # 402-ML) stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED 50 for this effect is 0.1-0.4 ng/mL. SDS-PAGE View Larger. 1 μg/lane of Recombinant Mouse IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a band (s) at 19 kDa. WebHuman IL-2 is synthesized as a 153-amino-acid precursor polypeptide and is then processed to mature IL-2. Mature human IL-2 is a 15.5 kDa four-alpha-helix bundle glycoprotein that consists of 133 amino acids.

WebLess than 0.01 ng endotoxin/1 μg hIL-2. Activity. The bioactivity of recombinant hIL-2 was determined in a CTLL-2 cell proliferation assay. The ED 50 of each lot is between 0.1 - …

WebInterleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. explain the 9 stage positionsWebProteini. Full gene name according to HGNC. Interleukin 13 receptor subunit alpha 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. IL13RA2 (CD213a2, CT19, IL-13R, IL13BP) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. b\u0026w bookshelf speakers for saleWebInterleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and … b\u0026w bowers \u0026 wilkins cm centre 2WebA novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice. View PDF In Frontiers in Immunology on … explain the 9th amendment for kidsWebInterleukin-2, T-cell growth factor, IL2_HUMAN. UniProt Code History. P60568. Gene. IL2, IL-2, TCGF, lymphokine. Bioactivity. The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Purification Method. SDS-PAGE & HPLC >= 98% explain the 9 protected characteristicsWebHuman IL-2 acts on murine and human T cells, and its receptors are shared by other cytokines. IL-2Rα is an IL-2–specific receptor, IL-2Rβ is shared with IL-15 and the γ chain that is a common receptor shared by many cytokines including IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. ... IL-2 UniProt View information about IL-2 on UniProt.org ... b\\u0026w boathouse inn moulsford ltdWebUseful information about the gene from Entrez. The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This p rotein binds … explain the abcd rule