Caroli disease (communicating cavernous ectasia, or congenital cystic dilatation of the intrahepatic biliary tree) is a rare inherited disorder characterized by cystic dilatation (or ectasia) of the bile ducts within the liver. There are two patterns of Caroli disease: focal or simple Caroli disease consists … See more The first symptoms typically include fever, intermittent abdominal pain, and an enlarged liver. Occasionally, yellow discoloration of the skin occurs. Caroli disease usually occurs in the presence of other diseases, … See more Modern imaging techniques allow the diagnosis to be made more easily and without invasive imaging of the biliary tree. Commonly, the disease is limited to the left lobe of the liver. Images taken by CT scan, X-ray, or MRI show enlarged intrahepatic (in the liver) bile … See more Mortality is indirect and caused by complications. After cholangitis occurs, patients typically die within 5–10 years. See more Jacques Caroli, a gastroenterologist, first described a rare congenital condition in 1958 in Paris, France. He described it as "nonobstructive saccular or fusiform multifocal … See more The cause appears to be genetic; the simple form is an autosomal dominant trait, while the complex form is an autosomal recessive trait. … See more The treatment depends on clinical features and the location of the biliary abnormality. When the disease is localized to one hepatic lobe, hepatectomy relieves symptoms and appears to remove the risk of malignancy. Good evidence suggests that malignancy … See more Caroli disease is typically found in Asia, and diagnosed in persons under the age of 22. Cases have also been found in infants and adults. … See more WebCaroli's disease, or communicating cavernous ectasia of the intrahepatic bile ducts, is an autosomal recessive disorder and is among the ductal plate malformations that occur at …
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Caroli disease - Wikipedia
WebJun 16, 2024 · DPMs represent a category of diseases involving abnormal formation of intrahepatic ducts, such as von Meyenburg complex, congenital hepatic fibrosis, Caroli disease, Caroli syndrome and polycystic kidney disease (Hepatology 1992;16:1069, Mayo Clin Proc 1998;73:80) WebMar 28, 2024 · Caroli disease is a congenital disorder characterized by multifocal, segmental dilatation of large intrahepatic bile ducts . The condition is usually associated … WebJul 14, 2024 · By 1996, the Karolyis had become U.S. citizens and were preparing for the Atlanta Games with their own club athletes. But instead of training 18-year-old Kerri Strug and 14-year-old Dominique ... harwal seal cross reference